Complex STAT1:TNFR1* map
Complex composition:

  1. TNFR1* map
  2. STAT1 map

STAT1|​pho:​TNFR1*@Membrane

Identifiers
NAME:STAT1:TNFR1*

Maps_Modules

References
PMID:14607933
TNF induces the association of STAT-1 and TNFR1 in a tyrosine phosphorylation-independent manner, and and this association attenuates TNF-alpha-mediated NF-kappaB activation but formation of the TNFR1:STAT-1?? complex is inhibited upon inclusion of IFNG . IFNG limits STAT-1 availability to the TNFR1 by depleting STAT from the cytoplasm, thus allowing for optimal NF-kappaB activation upon TNF ligation.

Modifications:
Participates in complexes:
In compartment: Membrane
  1. STAT1|​pho:​TNFR1*@Membrane map
Participates in reactions:
As Reactant or Product:
  1. STAT1|​pho|​active@Cytosol map + TNFR1*@Membrane map → map STAT1|​pho:​TNFR1*@Membrane map
As Catalyser: