Identifiers
HUGO:MAPK3 HGNC:6877 ENTREZ:5595 UNIPROT:P27361 GENECARDS:MAPK3 HUGO:MAPK1 HGNC:6871 ENTREZ:5594 UNIPROT:P28482 GENECARDS:MAPK1 HUGO:MAPK6 HGNC:6879 ENTREZ:5597 UNIPROT:Q16659 GENECARDS:MAPK6 HUGO:MAPK4 HGNC:6878 ENTREZ:5596 UNIPROT:P31152 GENECARDS:MAPK4
Maps_Modules
MODULE:MACROPHAGE
MODULE:CORE_SIGNALING_PATHWAYS
References
KEGG:5595 ATLASONC:MAPK3ID425ch16p11 WIKI:MAPK3
REACTOME:59283 KEGG:5594 ATLASONC:MAPK1ID41288ch22q11 WIKI:MAPK1
KEGG:5597 ATLASONC:MAPK6ID43349ch15q21 WIKI:MAPK6
KEGG:5596 ATLASONC:MAPK4ID41293ch18q21 WIKI:MAPK4
PMID:16713974
TLR2 activates (induces phosphorylation of) ERKs, JNKs, and p38 rapidly and transiently in control macrophages.
This activation is inhibited by IFNG signaling.
Production of IL10 is partially ERK dependent.
Identifiers
Maps_Modules
References
ERK*@CytosolIdentifiers
Maps_Modules
References
PMID:16713974
TLR2 activates (induses phosphorylation of) ERKs, JNKs, and p38 rapidly and transiently in control macrophages.