Protein RBCK1 map

Identifiers
HUGO:RBCK1

Maps_Modules
MODULE:MACROPHAGE
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS

References
PMID:24699077
LUBAC, linear ubiquitin chain assembly complex comprises????SHANK-associated RH-domain interactor (SHARPIN), heme-oxidized IRP2 ubiquitin ligase 1 homolog (HOIL1/RBCK1) and the E3 HOIL-1???interacting protein (HOIP/RNF31)
???is recruited to the TNFR1 complex via binding to the autoubiquitinated c-IAP1 and c-IAP2 proteins to mediate the assembly of linear polyubiquitin chains on NF-??B essential modifier (NEMO/IKBKG) and RIPK1


Modifications:
Participates in complexes:
In compartment: Cytosol
  1. RBCK1:​RNF31:​SHARPIN@Cytosol map
Participates in reactions:
As Reactant or Product:
    As Catalyser:
    1. CHUK:​IKBKG:​IKK_beta_*@Cytosol map map CHUK:​IKBKG|​ubi:​IKK_beta_*|​pho@Cytosol map