Protein IRF5 map

Identifiers
HUGO:IRF5

Maps_Modules
MODULE:MACROPHAGE
MODULE:CORE_SIGNALING_PATHWAYS

References
PMID:23390297
MIF inhitits expression of M1 markers such as IRF5
PMID:21240265
High expression of IRF5 was characteristic of M1 macrophages, in which it directly activated transcription of the genes encoding interleukin 12 subunit p40 (IL-12p40), IL-12p35 and IL-23p19 and repressed the gene encoding IL-10.

IRF5@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. IRF5@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rIRF5@Cytosol map → map IRF5@Cytosol map
    As Catalyser:
    1. gIL12p35*@Cytosol map → map rIL12p35*@Cytosol map
    2. gIL10@Cytosol map → map rIL10@Cytosol map
    3. gIL23A@Cytosol map → map rIL23A@Cytosol map
    4. gIL12p40*@Cytosol map → map rIL12p40*@Cytosol map