Protein cIAP* map

Identifiers
HUGO:BIRC2 HUGO:BIRC3

Maps_Modules
MODULE:MACROPHAGE
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS

References
PMID:21232017, PMID:21133840, PMID:17301840
cIAP1 and cIAP2 modify RIP1, TRAF2 and themselves with K63-linked ubiquitin chains. This creates docking sites for the LUBAC complex, an E3 ligase capable of forming linear polyubiquitin chains.

cIAP*@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. cIAP*@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. BIRC2@Cytosol map → map cIAP*@Cytosol map
    2. BIRC3@Cytosol map → map cIAP*@Cytosol map
    As Catalyser:
    1. FADD:​RIPK1:​TNF:​TNFR1*:​TRADD:​TRAF2@Membrane map → map FADD:​RIPK1|​ubi:​TNF:​TNFR1*:​TRADD:​TRAF2|​ubi@Membrane map