Protein BIRC2 map

Identifiers
HUGO:BIRC2

Maps_Modules
MODULE:MACROPHAGE
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS

References
PMID:21232017, PMID:21133840, PMID:17301840
cIAP1 and cIAP2 modify RIP1, TRAF2 and themselves with K63-linked ubiquitin chains. This creates docking sites for the LUBAC complex, an E3 ligase capable of forming linear polyubiquitin chains.

BIRC2@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. BIRC2@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. BIRC2@Cytosol map → map cIAP*@Cytosol map
    As Catalyser: