Protein IL1R1
HUGO:IL1R
MODULE:MDSC
MODULE:IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS
PMID:18977329
IL-1?? activates MDSC in vitro and in vivo through an IL-1RI/NF-??B pathway.

---

Modifications:
Participates in complexes:
In compartment: Membrane

1. IL1R1:​IL1RAP@Membrane
2. IL1R1:​IL1RAP:​trILB1@Membrane

Participates in reactions:
As Reactant or Product:

1. IL1R1:​IL1RAP:​trILB1@Membrane → Migration into tumor@default
2. trILB1@default + IL1R1:​IL1RAP@Membrane → IL1R1:​IL1RAP:​trILB1@Membrane

As Catalyser:

1. rRELA@Cytosol → RELA@Cytosol