Protein AKT* map

Identifiers
HUGO:AKT1
HUGO:AKT2
HUGO:AKT3

Maps_Modules
MODULE:MACROPHAGE
MODULE:CORE_SIGNALING_PATHWAYS

References
PMID:11687500
Binding to second messenger lipids allows PDK1 and AKT (PKB) to interact with each other, resulting in the phosphorylation and consequent activation of AKT (PKB).

AKT*|​pho|​active@Cytosol

Identifiers

Maps_Modules

References
PMID:16713974
AKT kinases phosphorylate GSK3 proteins and inhibit its activity downstream of TLR signaling.
IFNG prevents this inactivation.

AKT*@Cytosol

Identifiers

Maps_Modules

References

Modifications:
In compartment: Cytosol
  1. AKT*@Cytosol map
  2. AKT*|​pho|​active@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. AKT*@Cytosol map → map AKT*|​pho|​active@Cytosol map
    As Catalyser:
    1. gMRC1@Cytosol map → map rMRC1@Cytosol map
    2. GSK3_beta_*@Cytosol map → map GSK3_beta_*|​pho@Cytosol map
    3. GSK3_alpha_*@Cytosol map → map GSK3_alpha_*|​pho@Cytosol map