Protein PTPRC map

Identifiers
HUGO:PTPRC

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / SMAC  map

References
PMID:23886063 PMID:23620508 PMID:23620508?? PMID:19290918 PMID:12414720??
CASCADE:SLAMF7
 NATURAL_KILLER  map
INPUT_ACTIVATORS
PMID:25312647
CD45 is required for the activating function of SLAMF7 but not of 2B4 in NK cells.

Modifications:
In compartment: dSMAC
  1. PTPRC@dSMAC map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. CD247:​CD3*:​alpha_/beta_TCR*@cSMAC map → map CD247|​pho:​CD3*|​pho:​alpha_/beta_TCR*@cSMAC map + PTPRC@dSMAC map
    As Catalyser:
    1. FYN|​Y528_pho@cSMAC map → map FYN@T_cell map
    2. CD247|​pho:​CD3*|​pho:​alpha_/beta_TCR*@cSMAC map → map CD247:​CD3*:​alpha_/beta_TCR*@cSMAC map
    3. LCK|​Y505_pho@cSMAC map → map LCK@cSMAC map