Simple molecule PIP3* map
PIP3*@T_cell

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / TCR_SIGNALING  map

References
PMID:12040186 PMID:9438848 PMID:12670391 PMID:11526404

Modifications:
In compartment: T_cell
  1. PIP3*@T_cell map
Participates in complexes:
In compartment: T_cell
  1. ITK:​PIP3*@T_cell map
  2. PIP3*:​TEC@T_cell map
  3. PIP3*:​TXK@T_cell map
  4. PDPK1:​PIP3*@T_cell map
  5. PIP3*:​TXK|​pho@T_cell map
  6. (ITK|​pho:​PIP3*)|​active@T_cell map
  7. (PIP3*:​TEC|​pho)|​active@T_cell map
In compartment: cSMAC
  1. PDPK1:​PIP3*@cSMAC map
Participates in reactions:
As Reactant or Product:
  1. PIP2*@T_cell map → map PIP3*@T_cell map
  2. PDPK1@T_cell map + PIP3*@T_cell map → map PDPK1:​PIP3*@T_cell map
  3. PIP3*@T_cell map → map PIP2*@T_cell map
  4. ITK:​PIP3*@T_cell map → map (ITK|​pho:​PIP3*)|​active@T_cell map
  5. PDPK1:​PIP3*@T_cell map → map PDPK1:​PIP3*@cSMAC map
  6. TEC@T_cell map + PIP3*@T_cell map → map PIP3*:​TEC@T_cell map
  7. PIP3*:​TEC@T_cell map → map (PIP3*:​TEC|​pho)|​active@T_cell map
  8. PIP3*@T_cell map + ITK@T_cell map → map ITK:​PIP3*@T_cell map
  9. PIP3*:​TXK@T_cell map → map PIP3*:​TXK|​pho@T_cell map
  10. PIP3*@T_cell map + TXK@T_cell map → map PIP3*:​TXK@T_cell map
As Catalyser:
  1. AKT*|​Thr450_pho@T_cell map → map AKT*|​Thr308_pho|​Thr450_pho@T_cell map
  2. VAV1@T_cell map → map VAV1|​pho|​active@T_cell map
  3. DAG:​PRKCQ@cSMAC map → map (DAG:​PRKCQ|​pho)|​active@cSMAC map
  4. gIFNG@T_cell map → map rIFNG@T_cell map
  5. LAT@T_cell map + PLCG1@T_cell map + GRB2@T_cell map + GRAP2@T_cell map + GRAP@T_cell map → map GRAP:​GRAP2:​GRB2:​LAT|​pho:​PLCG1@T_cell map
  6. GRAP:​GRAP2:​GRB2:​LAT|​pho:​PLCG1@T_cell map → map GRAP:​GRAP2:​GRB2:​LAT|​pho:​PLCG1|​pho@T_cell map