Protein AURKA
Identifiers
aurora kinase A
HUGO:AURKA, HGNC:11393, ENTREZ:6790, UNIPROT:O14965
Maps_Modules
HMC:SUSTAINING_PROLIFERATIVE_SIGNALLING
Cell Cycle DNA Repair
/ G2_M_CHECKPOINT
References
AURKA phosphorylates and activates CDC25B on Ser339 to allow G2/M transition
PMID:19075565, PMID:20011137
Modifications:
In compartment: Nucleus
- AURKA@Nucleus
Participates in complexes:
In compartment: Nucleus
- AURKA:BRCA1|S308_pho@Nucleus
Participates in reactions:
As Reactant or Product:- BRCA1|S308_pho@Nucleus
+ AURKA@Nucleus
→
AURKA:BRCA1|S308_pho@Nucleus
As Catalyser:- CDC25B@Nucleus
→
CDC25B|S353_pho|active@Nucleus
- BRCA1@Nucleus
→
BRCA1|S308_pho@Nucleus