Reaction known_transition_omitted em_emtc_emtc_re931 map

ARHGAP35@Cytosol map → ARHGAP35|​pho@Cytosol map

Reaction regulators:
Catalysis
  1. PTK6@Cytosol map
  2. c-SRC*|​Y_pho|​active@Cytosol map


References
PMID:18829532
PMID:9819392
PTK6 and CSK both can phosphorylate ARHGAP35 (p190) at Y1105
RasGAP actvity of RASA1 is reduced when associated with ARHGAP35 which is a specific GAP for RhoA
ARHGAP35 is tyrosine-phosphorylated.
The association of ARHGAP35 (p190) with RASA1 (p120) is promoted and stabilized by phosphorylation of p190 at Y1105 by CSK or by PTK6.