Reaction known_transition_omitted em_emtc_emtc_re838 map

MCF2@Cytosol map MCF2|​pho|​active@Cytosol map

Reaction regulators:
Catalysis
  1. TNK2@Cytosol map
Inhibition
  1. NME1@Cytosol map


References
PMID:11394904
PMID:10652228
GEF activity of MCF2 (DBL) towards CDC42 or Rac1 is enhanced upon TNK2 (ACK1) phosphorylation.
PMID:18470881
Nm23-H1 binds Dbl-1 and thus interferes with the ability of Dbl-1 to load GTP onto CDC42