Protein LGR5
Identifiers
leucine-rich repeat containing G protein-coupled receptor 5
"G protein-coupled receptor 49", GPR49, GPR67, "leucine-rich repeat-containing G protein-coupled receptor 5"
HUGO:LGR5 HGNC:4504 ENTREZ:8549 UNIPROT:O75473 GENECARDS:LGR5 KEGG:8549 ATLASONC:GC_LGR5 WIKI:LGR5
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ WNT_NON_CANONICAL
LGR5@Cytoplasm
References
s_wnc1_re18:( Survival
) PMID:21693646
Modifications:
In compartment: Cytoplasm
- LGR5@Cytoplasm
Participates in complexes:
In compartment: Cytoplasm
- LGR5:RSPO1-4*@Cytoplasm
- CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:LGR5:LRP5_6*:RSPO1-4*:WNT*:p120*@Cytoplasm
Participates in reactions:
As Reactant or Product:- RSPO1-4*@default
+ LGR5@Cytoplasm
→
LGR5:RSPO1-4*@Cytoplasm
- LGR5:RSPO1-4*@Cytoplasm
+ CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:LRP5_6*:WNT*:p120*@Cytoplasm
→
CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:LGR5:LRP5_6*:RSPO1-4*:WNT*:p120*@Cytoplasm
- CK1_epsilon_*:E-Cadherin*:FZD*:GTP:G_alpha_*:G_beta_*:G_gamma_*:LGR5:LRP5_6*:RSPO1-4*:WNT*:p120*@Cytoplasm
→
WNT canonical pathway@Cytoplasm
As Catalyser: