Protein RSPO1-4* map

Identifiers
R-spondin 1
HUGO:RSPO1 HGNC:21679 ENTREZ:284654 UNIPROT:Q2MKA7 GENECARDS:RSPO1 KEGG:284654 ATLASONC:RSPO1ID44137ch1p34 WIKI:RSPO1
R-spondin 2
HUGO:RSPO2 HGNC:28583 ENTREZ:340419 UNIPROT:Q6UXX9 GENECARDS:RSPO2 KEGG:340419 ATLASONC:GC_RSPO2 WIKI:RSPO2
R-spondin 3
HUGO:RSPO3 HGNC:20866 ENTREZ:84870 UNIPROT:Q9BXY4 GENECARDS:RSPO3 KEGG:84870 ATLASONC:GC_RSPO3 WIKI:RSPO3
R-spondin 4
HUGO:RSPO4 HGNC:16175 ENTREZ:343637 UNIPROT:Q2I0M5 GENECARDS:RSPO4 KEGG:343637 WIKI:RSPO4

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_NON_CANONICAL  map

RSPO1-4*@default

References
s_wnc1_re18:( Survival  map ) PMID:21693646

Modifications:
In compartment: default
  1. RSPO1-4*@default map
Participates in complexes:
In compartment: Cytoplasm
  1. LGR5:​RSPO1-4*@Cytoplasm map
  2. CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LGR5:​LRP5_6*:​RSPO1-4*:​WNT*:​p120*@Cytoplasm map
Participates in reactions:
As Reactant or Product:
  1. RSPO1-4*@default map + LGR5@Cytoplasm map → map LGR5:​RSPO1-4*@Cytoplasm map
  2. LGR5:​RSPO1-4*@Cytoplasm map + CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LRP5_6*:​WNT*:​p120*@Cytoplasm map → map CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LGR5:​LRP5_6*:​RSPO1-4*:​WNT*:​p120*@Cytoplasm map
  3. CK1_epsilon_*:​E-Cadherin*:​FZD*:​GTP:​G_alpha_*:​G_beta_*:​G_gamma_*:​LGR5:​LRP5_6*:​RSPO1-4*:​WNT*:​p120*@Cytoplasm map → map WNT canonical pathway@Cytoplasm map
As Catalyser: