Phenotype modulaton of ion fluxes map
modulaton of ion fluxes@Inflammasome platforms

Identifiers
Pyroptosis

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / PYROPTOSIS  map

References
PMID:26885855
PMID:27048821
the amino-terminal gasdermin D
domain may oligomerize to form a membrane pore akin to
how MLKL may act during necroptosis [80, 81]. Alternatively, the pyroptotic gasdermin D domain may induce cell
lysis indirectly by damaging intracellular organelles that
result in disruption of mitochondrial respiration and ATP
synthesis
PMID:27066895

Modifications:
In compartment: Inflammasome platforms
  1. modulaton of ion fluxes@Inflammasome platforms map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. Pyroptosis@Inflammasome platforms map → map modulaton of ion fluxes@Inflammasome platforms map
    As Catalyser: