Protein ITGB6 map

Identifiers
integrin subunit beta 6
HUGO:ITGB6 hgnc_id:HGNC:6161 HGNC:6161 ENTREZ:3694 UNIPROT:P18564
integrin, beta 6
HUGO:ITGB6 HGNC:6161 ENTREZ:3694 UNIPROT:P18564

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map
 EMT Senescence  map  / ECM  map

References
CASCADE:INTEGRIN
PMID:23673986
Expression of fibronectin receptro ??v??6 in CAFs is a negative factor for patient survival.
PMID:26519775
The ??v-containing integrins ??v??1, ??v??3, ??v??5, and ??v??6 in a variety of fibroblasts and pericytes are reported to activate latent TGF-?? by binding to the RGD motif of the latency-associated protein (LAP) that is bound to TGF-?? and the latent TGF-?? binding protein (LTBP) forming the large latent complex (LLC

Modifications:
In compartment: Cytosol
  1. ITGB6@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. ITGAV@Cytosol map + ITGB6@Cytosol map → map ca_s4779
    2. rITGB6@Nucleus map → map ITGB6@Cytosol map
    3. ITGAV@Cytosol map + ITGB6@Cytosol map → map em_emtc_emtc_s3141
    As Catalyser: