Protein ETS2 map

Identifiers
ETS proto-oncogene 2, transcription factor
HUGO:ETS2 hgnc_id:HGNC:3489 HGNC:3489 ENTREZ:2114 UNIPROT:P15036
HUGO:ETS2

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / CORE  map
HMC:ENABLING_REPLICATION_AND_IMMORTALITY
 Telomere Maintenance  map  / TELOMERASE  map

References
PMID:19847259
In fibroblasts PTEN inhibit ETS2 expression; and AKT and JNK induce phosphorylqtion of ETS2. MMP9 and CCL3 are the direct targets of this transcription factor.
PMID:23977064
Ets2 in tumor fibroblasts promotes angiogenesis in breast cancer

Modifications:
In compartment: Cytosol
  1. ETS2@Cytosol map
  2. ETS2|​pho|​active@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. rETS2@Cytosol map → map ETS2@Cytosol map
    2. ETS2@Cytosol map → map ETS2|​pho|​active@Cytosol map
    As Catalyser:
    1. gCCL3@Cytosol map → map rCCL3@Cytosol map
    2. gMMP9@Cytosol map → map rMMP9@Cytosol map