Phenotype ERAD
ERAD@Cytosol
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ ER_STRESS
References
PMID:23850759
ER-associated degradation
Modifications:
In compartment: Cytosol
- ERAD@Cytosol
Participates in complexes:
Participates in reactions:
As Reactant or Product:- XBP1@Cytosol
→
ERAD@Cytosol
- ERAD@Cytosol
→
accumulation of misfolded protein in ER@Endopasmic Reticulum
As Catalyser:- retrograde transport from ER to cytosol@Endopasmic Reticulum
→
protein ubiquitination and destruction@Cytosol
- Unfolded protein*@Proteasome
→
degraded