Protein RBPJ map

Identifiers
HUGO:RBPJ

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / CAF_INHIBITION_ANTITUMOR  map

References
PMID:26302407
CSL (RBPJ) as a common repressor of fibroblast senescence and CAF activation
CSL may affect p53 activity through physical interaction.
Levels of CSL, p53 and CDKN1A expression were all significantly decreased in lesion-adjacent stroma versus distant unaffected skin

Modifications:
In compartment: Cytosol
  1. RBPJ@Cytosol map
Participates in complexes:
In compartment: Cytosol
  1. RBPJ:​TP53@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. TP53@Cytosol map + RBPJ@Cytosol map → map RBPJ:​TP53@Cytosol map
  2. RBPJ:​TP53@Cytosol map → map NEGATIVE_REGULATORS OF_CAF@Cytosol map
As Catalyser: