Protein HSF1 map

Identifiers
HUGO:HSF1

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / FIBROBLAST_ACTIVATION_MARKERS  map

References
PMID:25083868
The transcriptional regulator Heat-Shock Factor 1 (HSF1) is frequently activated in cancer-associated fibroblasts (CAFs)
The effects of stromal HSF1 activation on cancer cells are mediated by TGF?? and SDF1 signaling,
expression levels of Sdf1, Tgf??1 and Tgf??2 were significantly lower in Hsf1 null MEFs than in WT MEFs, even without co-culture with cancer cells

Modifications:
In compartment: Cytosol
  1. HSF1@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. gTGFB*@Cytosol map → map rTGFB*@Cytosol map
      2. gCXCL12@Cytosol map → map rCXCL12@Cytosol map