RNA CXCL12 map

Identifiers
HUGO:CXCL12

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / CYTOKINES_CHEMOKINES_PRODUCTION  map

References
CASCADE:TGFB
CASCADE:HGF
PMID:23034983
TGFB upregulates gene expression of CAF markers ,??FSP1 (S100A4), and??TNC. (provably via SMAD3), and gene expression of CCL5, SDF1(CXCL12), BMP4, IL6, CXCL7, IL6R, IL6ST, CXCL5
PMID:23402812
Hepatocyte growth factor activates tumor stromal fibroblasts to promote tumorigenesis in gastric cancer.
HGF induces expression markers of activated fibroblasts such as FAP, CXCL12 (SDF1),aplpha-SMA

Modifications:
In compartment: Cytosol
  1. rCXCL12@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gCXCL12@Cytosol map → map rCXCL12@Cytosol map
    2. rCXCL12@Cytosol map → map CXCL12@Cytosol map
    As Catalyser: