Protein STC1 map

Identifiers
HUGO:STC1

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / GROWTH_FACTORS_PRODUCTION  map

References
CASCADE:PDGF
PMID:23243022
Quantitative real-time PCR (qRT-PCR) analyses of STC1 expression confirmed a 15-fold STC1-induction upon PDGF stimulation of fibroblasts
STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer
STC1-deficient fibroblasts displayed reduced intravasation of tumor cells along with fewer and smaller distant metastases formed.

Modifications:
In compartment: Cytosol
  1. STC1@Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. STC1@Cytosol map → map TUMOR_INVASION@default map
    2. rSTC1@Cytosol map → map STC1@Cytosol map
    As Catalyser: