Identifiers
microRNA 107
HUGO:MIR107 HGNC:31496 ENTREZ:406901
References
rc_re1200( Regulated Cell Death ):
PMID:20308559
bioinformatic prediction
in HCT116, expression of MIR107 precursor decreases ARNT protein abundance
in HCT116, in Hela, in SW480, RNA antisens to MIR107 increases ARNT protein abundance
+ luciferase reporter assay using the 3'UTR of ARNT
in HCT116, knockdown of endogenous miR-107 increased desferrioxamine(hypoxia mimick)-induced VEGF levels, which is rescued by a expression of ARNT lacking its 3'UTR.
in HCT116, pre-miR-107 decreases the ability of HCT116 cells to stimulate endothelial proliferation upon hypoxia (MMT assay)