Reaction translation rc_re1200 map

rHIF1B*@Nucleus map → HIF1B*@Nucleus map

Reaction regulators:
Inhibition
  1. arMIR107@Cytosol map


References
PMID:20308559
bioinformatic prediction
in HCT116, expression of MIR107 precursor decreases ARNT protein abundance
in HCT116, in Hela, in SW480, RNA antisens to MIR107 increases ARNT protein abundance
+ luciferase reporter assay using the 3'UTR of ARNT
in HCT116, knockdown of endogenous miR-107 increased desferrioxamine(hypoxia mimick)-induced VEGF levels, which is rescued by a expression of ARNT lacking its 3'UTR.
in HCT116, pre-miR-107 decreases the ability of HCT116 cells to stimulate endothelial proliferation upon hypoxia (MMT assay)