Identifiers
HUGO:MMP13
matrix metallopeptidase 13 (membrane-inserted)
HUGO:MMP13, HGNC:7159, ENTREZ:4322, GENECARDS:GC11M102847??
matrix metallopeptidase 13 (collagenase 3)
"matrix metalloproteinase 13 (collagenase 3)"
HUGO:MMP13 HGNC:7159 ENTREZ:4322 UNIPROT:P45452
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / ECM
HMC:EVADING_GROWTH_SUPPRESSORS
Survival / MAPK
References
CASCADE:INTEGRIN
PMID:17420280
Analysis of matrix metalloproteinase in vitro and in vivo revealed disturbed MMP13 and MMP14 synthesis in alpha11(-/-) cells.
References
em_emtc_emtc_re309( EMT Senescence ):
PMID:19564415
The transcription factor FOXO3, negatively regulated by binding to 14-3-3 protein family, induces MMP9 and MMP13 expression.
This explains the role of FOXO3 in promoting tumor invasion.