RNA MMP13 map

Identifiers
HUGO:MMP13
matrix metallopeptidase 13 (membrane-inserted)
HUGO:MMP13, HGNC:7159, ENTREZ:4322, GENECARDS:GC11M102847??

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / MATRIX_REGULATION  map
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map

References
CASCADE:INTEGRIN
PMID:17420280
Analysis of matrix metalloproteinase in vitro and in vivo revealed disturbed MMP13 and MMP14 synthesis in alpha11(-/-) cells.

rMMP13@Nucleus

References
em_emtc_emtc_re309( EMT Senescence  map ):
PMID:19564415
The transcription factor FOXO3, negatively regulated by binding to 14-3-3 protein family, induces MMP9 and MMP13 expression.
This explains the role of FOXO3 in promoting tumor invasion.

Modifications:
In compartment: Cytosol
  1. rMMP13@Cytosol map
In compartment: Nucleus
  1. rMMP13@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gMMP13@Cytosol map → map rMMP13@Cytosol map
    2. rMMP13@Cytosol map → map MMP13@Cytosol map
    3. gMMP13@Nucleus map → map rMMP13@Nucleus map
    4. rMMP13@Nucleus map → map MMP13@Cytosol map
    As Catalyser: