Identifiers
HUGO:PTEN
phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
HUGO:PTEN, HGNC:9588, ENTREZ:5728, UNIPROT:P60484, GENECARDS:GC10P089613
phosphatase and tensin homolog
HUGO:PTEN HGNC:9588 ENTREZ:5728 UNIPROT:P60484
HUGO:PTEN HGNC:9588 ENTREZ:5728 UNIPROT:P60484 GENECARDS:PTEN REACTOME:62405 KEGG:5728 ATLASONC:PTENID158 WIKI:PTEN
phosphatase and tensin homo

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts   / CAF_INHIBITION_ANTITUMOR 
 Cancer Associated Fibroblasts   / CORE 
 EMT Senescence   / EMT_REGULATORS 
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death   / APOPTOSIS 
 Regulated Cell Death   / STARVATION_AUTOPHAGY 
 Regulated Cell Death   / DEATH_RECEPTOR_PATHWAYS 
 Regulated Cell Death   / DEPENDANCE_RECEPTORS 
 Regulated Cell Death   / RCD_GENES 
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival   / HEDGEHOG 
 Survival   / PI3K_AKT_MTOR 

References
PMID:25364523
We cultured cardiac fibroblasts of mice were in hypoxia or normoxia conditions for 12, 24 and 48 hours. At all the time points, caveolin-1 and PTEN expression were gradually reduced, whereas, ??-SMA was gradually increased.
PMID:12040186
PMID:16288286
PMID:17218262

References
mo_re194:( motility  ) PMID:22677902

1. rPTEN@Cytosol

1. rPTEN@Nucleus

1. MIR21:​PTEN@Nucleus
2. MIR19A:​PTEN@Nucleus

1. rPTEN@Cytosol → PTEN@Cytosol
2. gPTEN@Nucleus → rPTEN@Nucleus
3. rPTEN@Nucleus → PTEN@Cytosol
4. gPTEN@Nucleus → rPTEN@Nucleus
5. rPTEN@Nucleus → PTEN@Nucleus
6. arMIR21@Nucleus + rPTEN@Nucleus → MIR21:​PTEN@Nucleus
7. arMIR19A@Nucleus + rPTEN@Nucleus → MIR19A:​PTEN@Nucleus
8. gPTEN@Nucleus → rPTEN@Nucleus
9. rPTEN@Nucleus → PTEN@Cytosol
10. arMIR214@Nucleus + rPTEN@Nucleus → su_akt1_s_akt2_s416
11. arMIR29B*@Nucleus + rPTEN@Nucleus → su_shh1_s_shh2_s250
12. arMIR29B*@Nucleus + rPTEN@Nucleus → su_shh1_s_shh2_s250

1. rPTEN@Nucleus → PTEN@Nucleus