Identifiers
HUGO:PTCH1 HUGO:PTCH2
Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
Cancer Associated Fibroblasts / GROWTH_FACTORS_SIGNALING_PATHWAYS
References
CASCADE:HH
PMID:22354771; PMID:17638910
Stimulation of cultured normal fibroblasts with TGF?? in the absence of SHH increased the mRNA levels of the hedgehog target genes Ptch1, Ptch2 (probably via GLI1 and GLI2)