Phenotype WNT3 stimulation
WNT3 stimulation@Extracellular space
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ WNT_CANONICAL
References
s_wca2_re59:( Survival
) PMID:23371553
s_wca2_re60( Survival
):
Without RIPK4 upon wnt3 stimulation 25% of HeLa cells show DVL2 in puncta. Co-transfection of RIPK4 increases this number to more than 75%
PMID:23371553
Modifications:
In compartment: Extracellular space
- WNT3 stimulation@Extracellular space
Participates in complexes:
Participates in reactions:
As Reactant or Product:
As Catalyser:- DVL2:RIPK4@Cytoplasm
→
DVL2|S480_pho|S298_pho:RIPK4@Cytoplasm
- DVL2|S480_pho|S298_pho:RIPK4@Cytoplasm
+ LRP6@Cytoplasm
→
DVL2|S480_pho|S298_pho:LRP6:RIPK4@Cytoplasm