Complex DVL2:LRP6:RIPK4
Complex composition:
- RIPK4
- DVL2
- LRP6
DVL2|S480_pho|S298_pho:LRP6:RIPK4@Cytoplasm
Identifiers
NAME:DVL2:LRP6:RIPK4
Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ WNT_CANONICAL
References
s_wca2_re60( Survival
):
Without RIPK4 upon wnt3 stimulation 25% of HeLa cells show DVL2 in puncta. Co-transfection of RIPK4 increases this number to more than 75%
PMID:23371553
s_wca2_re61:( Survival
) continue with dvl puncta formation
Modifications:
Participates in complexes:
In compartment: Cytoplasm
- DVL2|S480_pho|S298_pho:LRP6:RIPK4@Cytoplasm
Participates in reactions:
As Reactant or Product:- DVL2|S480_pho|S298_pho:RIPK4@Cytoplasm
+ LRP6@Cytoplasm
→
DVL2|S480_pho|S298_pho:LRP6:RIPK4@Cytoplasm
- DVL2|S480_pho|S298_pho:LRP6:RIPK4@Cytoplasm
→
WNT canonical pathway@Cytoplasm
As Catalyser: