RNA LIN2* map

Identifiers
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
HUGO:CASK, HGNC:1497, ENTREZ:8573, GENECARDS:GC0XM041374????

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map

References
PMID:9753323
Heterotrimeric complex Lin2-Lin7-Lin10 (C. elegans)
PMID:9822620
human lin10 contains 2 PDZ domains
human lin10 interacts with mammalian lin2 (CASK)
mammalian lin7 interacts with mammalian lin2 (CASK)
heterotrimeric complex Lin2-lin7-Lin10 in mouse brain
PMID:9753324
Trimeric complex Lin2-Lin7-Lin10 in brain.
Each protein contains PDZ domains-not involved in complex formation
PMID:10871881
LIN2(CASK) contains two L27 domains, 1 PDZ domain, 1 SH3 domain, 1 inactive Guanylate Kinase domain
LIN7 contains one L27 domain, 1 PDZ domain
Interaction LIN2-LIN7 via L27 domain

rLIN2*@Nucleus

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CYTOSKELETON_POLARITY  map

References
PMID:9753323
Heterotrimeric complex Lin2-Lin7-Lin10 (C. elegans)
PMID:9822620
human lin10 contains 2 PDZ domains
human lin10 interacts with mammalian lin2 (CASK)
mammalian lin7 interacts with mammalian lin2 (CASK)
heterotrimeric complex Lin2-lin7-Lin10 in mouse brain
PMID:9753324
Trimeric complex Lin2-Lin7-Lin10 in brain.
Each protein contains PDZ domains-not involved in complex formation
PMID:10871881
LIN2(CASK) contains two L27 domains, 1 PDZ domain, 1 SH3 domain, 1 inactive Guanylate Kinase domain
LIN7 contains one L27 domain, 1 PDZ domain
Interaction LIN2-LIN7 via L27 domain

Modifications:
In compartment: Nucleus
  1. rLIN2*@Nucleus map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. gLIN2*@Nucleus map → map rLIN2*@Nucleus map
    2. rLIN2*@Nucleus map → map LIN2*@Cytosol map
    As Catalyser: