Complex GJA1_3_4_8_GJB2*:GJA3 map
Complex composition:

  1. GJA3 map
  2. GJA1_3_4_8_GJB2* map


GJA1_3_4_8_GJB2*:​GJA3@Neighbouring Cell

Identifiers
NAME:GJA1_3_4_8_GJB2*:GJA3

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / CELL_CELL_ADHESIONS  map
 EMT Senescence  map  / GAP_JUNCTIONS  map

References
GJA3 is so-called Connexin 46
PMID:8188753
Heterotypic channels composed of Cx46 (GJA3) paired with either Cx43 (GJA1) or Cx50 (GJA8) were also well coupled
Cx50 (GJA8) did not form functional channels with Cx43 (GJA1).
GJA8 is so-called Connexin 50
PMID:19646399
Connexins 46 and 50 combine to form the gap junctions in ocular lens fiber cells
18 phosphorylation sites on connexin 50 (GJA8) and 9 phosphorylation sites on connexin 46 (GJA3) were identified, all on serine or threonine residues.


Modifications:
Participates in complexes:
In compartment: Neighbouring Cell
  1. GJA1_3_4_8_GJB2*:​GJA3@Neighbouring Cell map
Participates in reactions:
As Reactant or Product:
  1. GJA1_3_4_8_GJB2*@Neighbouring Cell map + GJA3@Cytosol map map GJA1_3_4_8_GJB2*:​GJA3@Neighbouring Cell map
  2. GJA1_3_4_8_GJB2*:​GJA3@Neighbouring Cell map map Gap junctions@Cytosol map
As Catalyser: