Identifiers
NAME:GJA1_3_4_8_GJB2*:GJA3
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / CELL_CELL_ADHESIONS
EMT Senescence / GAP_JUNCTIONS
References
GJA3 is so-called Connexin 46
PMID:8188753
Heterotypic channels composed of Cx46 (GJA3) paired with either Cx43 (GJA1) or Cx50 (GJA8) were also well coupled
Cx50 (GJA8) did not form functional channels with Cx43 (GJA1).
GJA8 is so-called Connexin 50
PMID:19646399
Connexins 46 and 50 combine to form the gap junctions in ocular lens fiber cells
18 phosphorylation sites on connexin 50 (GJA8) and 9 phosphorylation sites on connexin 46 (GJA3) were identified, all on serine or threonine residues.