1. LTBP*
2. LAP
3. TGFB*

Identifiers
NAME:LAP:LTBP*:TGFB*

References
PMID:26519775; PMID:18086923; PMID:24309651
The ??v-containing integrins ??v??1, ??v??3, ??v??5, and ??v??8 in a variety of fibroblasts and pericytes are reported to activate latent TGF-?? by binding to the RGD motif of the latency-associated protein (LAP) that is bound to TGF-?? and the latent TGF-?? binding protein (LTBP) forming the large latent complex (LLC)

Identifiers
NAME:LAP:LTBP*:TGFB*

References
PMID:26519775; PMID:18086923; PMID:24309651
The ??v-containing integrins ??v??1, ??v??3, ??v??5, and ??v??8 in a variety of fibroblasts and pericytes are reported to activate latent TGF-?? by binding to the RGD motif of the latency-associated protein (LAP) that is bound to TGF-?? and the latent TGF-?? binding protein (LTBP) forming the large latent complex (LLC)

Identifiers
NAME:LAP:LTBP*:TGFB*

References
PMID:26519775; PMID:18086923; PMID:24309651
The ??v-containing integrins ??v??1, ??v??3, ??v??5, and ??v??8 in a variety of fibroblasts and pericytes are reported to activate latent TGF-?? by binding to the RGD motif of the latency-associated protein (LAP) that is bound to TGF-?? and the latent TGF-?? binding protein (LTBP) forming the large latent complex (LLC)

1. LAP:​LTBP*:​TGFB*@Cytosol

1. LAP:​LTBP*:​TGFB*@Treg modulation

1. LAP:​LTBP*:​TGFB*@default

1. LAP:​LTBP*:​TGFB*@Cytosol → GROWTH_FACTORS_PRODUCTION@default
2. LAP:​LTBP*:​TGFB*@default → TGFB*@default + LAP@default + LTBP*@default
3. TGFB*@Cytosol + LTBP*@Cytosol + LAP@Cytosol → LAP:​LTBP*:​TGFB*@Cytosol
4. LAP:​LTBP*:​TGFB*@Cytosol → LAP:​LTBP*:​TGFB*@default
5. LAP:​LTBP*:​TGFB*@Cytosol → LAP:​LTBP*:​TGFB*@Treg modulation