Identifiers
forkhead box O3
HUGO:FOXO3 HGNC:3821 ENTREZ:2309 UNIPROT:O43524
HUGO:FOXO3 HGNC:3821 ENTREZ:2309 UNIPROT:O43524 GENECARDS:FOXO3 REACTOME:199273 KEGG:2309 ATLASONC:AF6q21ID125 WIKI:FOXO3
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ APOPTOSIS
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death
/ RCD_GENES
HMC:EVADING_GROWTH_SUPPRESSORS
Survival
/ PI3K_AKT_MTOR
References
PMID:20673124
PMID:16288288
PMID:17646672
Identifiers
HGNC:3821
Maps_Modules
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ APOPTOSIS
Regulated Cell Death
/ STARVATION_AUTOPHAGY
Regulated Cell Death
/ DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death
/ RCD_GENES
References
rc_re192( Regulated Cell Death
):
PMID:18158893
in MEFs, in MCF7
rc_re193( Regulated Cell Death
):
PMID:19188590
in melanomas, correlation between MIR182 expression and progression from primary to metastatic melanoma, anticorrelation with FOXO3 level.
FOXO3 over-expression inhibits MIR182 metastatic effect
FOXO3 is a direct target of MIR182
BIM downregulated by MIR182 supposedly through FOXO3 inhibition