Identifiers
baculoviral IAP repeat containing 7
HUGO:BIRC7 HGNC:13702 ENTREZ:79444 UNIPROT:Q96CA5

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death   / APOPTOSIS 
 Regulated Cell Death   / CASPASES 

References
synonym:ML-IAP

Maps_Modules
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death   / APOPTOSIS 
 Regulated Cell Death   / CASPASES 

References
rc_re738( Regulated Cell Death  ):
PMID:11801603
in 293T, interaction between ectopically expressed proteins
in vitro, interaction between a DIABLO peptide and the BIR domain of ML-IAP
in 293T, binding of DIABLO to BIRC7 antagonizes the binding of processed CASP9
rc_re739( Regulated Cell Death  ):
in 293T, interaction of overexpressed proteins, by coIP

1. BIRC7@Cytosol

1. BIRC7:​DIABLO@Cytosol
2. BIRC7:​cleaved~Caspase9*@Cytosol

1. DIABLO@Cytosol + BIRC7@Cytosol → BIRC7:​DIABLO@Cytosol
2. BIRC7@Cytosol + cleaved~Caspase9*@Cytosol → BIRC7:​cleaved~Caspase9*@Cytosol