Protein ADAM10 map

Identifiers
ADAM metallopeptidase domain 10
HUGO:ADAM10, HGNC:188, ENTREZ:102, UNIPROT:O14672, GENECARDS:GC15M058887
HUGO:ADAM10

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map

References
PMID:19726682
PMID:19704010
PMID:19601831
 NATURAL_KILLER  map
PMID:22006996, PMID:18676862
Tumor-Associated MICA Is shed by ADAM10 and ADAM17 proteases. Downstream of HIF1 and hypoxia (ADAM10)

Modifications:
In compartment: TUMOR_CELL_AS_INDUCTOR
  1. ADAM10@TUMOR_CELL_AS_INDUCTOR map
Participates in complexes:
In compartment: Cytosol
  1. ADAM10:​ADAM17@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. rADAM10@TUMOR_CELL_AS_INDUCTOR map → map ADAM10@TUMOR_CELL_AS_INDUCTOR map
As Catalyser:
  1. DLL1:​NOTCH1@Neighbouring Cell map → map NICD*@Cytosol map