Protein a6b1*_a6b4* map

Identifiers
a6b1*_a6b4*
NAME:a6b1*
ITGA6/ITGB1
integrin, alpha 6
HUGO:ITGA6 HGNC:6142 ENTREZ:3655 UNIPROT:P23229
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
HUGO:ITGB1, HGNC:6153, ENTREZ:3688, UNIPROT:P05556, GENECARDS:GC10M033189
NAME:a6b4*
ITGA6/ITGB4
integrin, beta 4
HUGO:ITGB4 HGNC:6158 ENTREZ:3691 UNIPROT:P16144

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
PMID:22118458
Integrins a3b1, a6b1, a6b4 and a7b1 engage with laminins

a6b1*_a6b4*@Extracellular space

References
em_emtc_emtc_re921( EMT Senescence  map ):
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
PMID:10809728
Laminin-8 contains LAMA4, LAMB1, LAMC1
Laminin-8 interacts with integrins.

Modifications:
In compartment: Extracellular space
  1. a6b1*_a6b4*@Extracellular space map
Participates in complexes:
In compartment: Extracellular space
  1. Laminin8*:​a6b1*_a6b4*@Extracellular space map
Participates in reactions:
As Reactant or Product:
  1. a6b1*_a6b4*@Extracellular space map → map em_emtc_emtc_s3297
  2. a6b1*_a6b4*@Extracellular space map → map ITGA6:​ITGB4@Cytosol map
  3. Laminin8*@Extracellular space map + a6b1*_a6b4*@Extracellular space map → map Laminin8*:​a6b1*_a6b4*@Extracellular space map
  4. Laminin8*:​a6b1*_a6b4*@Extracellular space map → map Cell-matrix adhesions@Extracellular space map
As Catalyser: