Protein PDGFD map

Identifiers
platelet derived growth factor D
HUGO:PDGFD HGNC:30620 ENTREZ:80310 UNIPROT:Q9GZP0

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map

References
RTKs exist as inactive monomers; after binding to their ligands they form dimers and their intracellular domains are activated.
PMID:17496910
PMID:18403754
PMID:16607286

PDGFD@Extracellular space

References
em_emtc_emtc_re55( EMT Senescence  map ):
PMID:13130303
PMID:18403754
PMID:16607286
Keratin-14, 18, 19, Vimentin are putative direct HIF1 target genes
http://www.omicsonline.org/1948-5956/JCST-03-035.php
Genes induced by HIF-1 in cancer cells include KRT-14, 18, 19, Vimentin:
PMID:16077980
the NF-kappaB binding site is located in the human vimentin promoter.

Modifications:
In compartment: Extracellular space
  1. PDGFD@Extracellular space map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. PDGF family*@Extracellular space map → map PDGFD@Extracellular space map
    As Catalyser:
    1. gZO1*@Nucleus map → map rZO1*@Nucleus map
    2. gE-Cadherin*@Nucleus map → map rE-Cadherin*@Nucleus map
    3. gVimentin*@Nucleus map → map rVimentin*@Nucleus map