Protein PDGFA map

Identifiers
platelet-derived growth factor alpha polypeptide
HUGO:PDGFA HGNC:8799 ENTREZ:5154 UNIPROT:P04085

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map

References
RTKs exist as inactive monomers; after binding to their ligands they form dimers and their intracellular domains are activated.
PMID:17496910

Modifications:
In compartment: Cytosol
  1. PDGFA@Cytosol map
In compartment: Extracellular space
  1. PDGFA@Extracellular space map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. PDGF family*@Extracellular space map → map PDGFA@Extracellular space map
    2. rPDGFA@Nucleus map → map PDGFA@Cytosol map
    3. PDGFA@Cytosol map → map PDGFA@Extracellular space map
    As Catalyser: