Protein UBC9* map

Identifiers
Ubiquitin-conjugating enzyme E2I
HUGO:UBE21 GENECARDS:UBE21 WIKI:UBE21 HUGO:UBE2I HGNC:12485 ENTREZ:7329 UNIPROT:P63279 GENECARDS:UBE2I REACTOME:66763 KEGG:7329 ATLASONC:GC_UBE2I WIKI:UBE2I
"ubiquitin-conjugating enzyme E2I (homologous to yeast UBC9)", "ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)"
HUGO:UBE2I HGNC:12485 ENTREZ:7329 UNIPROT:P63279 GENECARDS:UBE2I REACTOME:66763 KEGG:7329 ATLASONC:GC_UBE2I WIKI:UBE2I HUGO:MSH6 HGNC:7329 ENTREZ:2956 UNIPROT:P52701 GENECARDS:MSH6 KEGG:2956 ATLASONC:MSH6ID344ch2p16 WIKI:MSH6

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / HEDGEHOG  map
 Survival  map  / WNT_NON_CANONICAL  map

References
PMID:20711444

UBC9*@Nucleus

References
s_wnc3_re16( Survival  map ):
Sequential sumoylion of NFAT1, might also occur in NFAT3 and 4. There is no special character for sumoylation in CellDesigner, so this is indicated by a "?". Lys684 is targeted firstly, followed by Lys897.
PMID:15117942
s_wnc3_re18( Survival  map ):
Order of sumoylation is not important.
PMID:19218564

UBC9*@Primary Cilium

References
s_shh1_re76( Survival  map ):
PMID:20711444
PTM=sumoylation N/A in CellDesigner.
Sumoylation not detected on endogenous Gli proteins.
PKA antagonise sumoylation due to the consequence of PKA phosphorylation on Gli proteins it is not a direct effect of PKA. Exact

Modifications:
In compartment: Nucleus
  1. UBC9*@Nucleus map
In compartment: Primary Cilium
  1. UBC9*@Primary Cilium map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
      As Catalyser:
      1. GLI2-185*|​pho|​active@Primary Cilium map → map GLI2-185*|​S805_unk|​pho|​active@Primary Cilium map
      2. GLI3-190*|​S849_emp|​active@Primary Cilium map → map GLI3-190*|​S849_emp|​S880_unk|​active@Primary Cilium map
      3. NFAT1*@Nucleus map → map NFAT1*|​unk@Nucleus map
      4. NFAT1*|​unk@Nucleus map → map NFAT1*|​unk|​unk@Nucleus map
      5. NFAT2*@Nucleus map → map NFAT2*|​K702_unk|​K914_unk@Nucleus map