Complex ITGAE:ITGB7 map
Complex composition:

  1. ITGB7 map
  2. ITGAE map

ITGAE:​ITGB7@Cytosol

Identifiers
NAME:ITGAE:ITGB7

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
PMID:17325197
Integrin aEb7 binds to E-Cadherin
This interaction promotes antitumor "killer T cell" activity by triggering lytic granule polarization and exocytosis.

ITGAE:​ITGB7@Cytosol

Identifiers
NAME:ITGAE:ITGB7

Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
 EMT Senescence  map  / EMT_REGULATORS  map
 EMT Senescence  map  / ECM  map
 EMT Senescence  map  / CELL_MATRIX_ADHESIONS  map

References
PMID:19161977
In the endoplasmic reticulum, integrin subunits find their binding partners and form heterodimers.
Monomeric integrins never reach the cell surface.
PMID:17325197
Integrin aEb7 binds to E-Cadherin
This interaction promotes antitumor "killer T cell" activity by triggering lytic granule polarization and exocytosis.
em_emtc_emtc_re334( EMT Senescence  map ):
PMID:11413131
E-cadherin dimerization is essential for adhesion to the integrin aEb7
Interaction between E-cadherin and aEb7 integrin plays major role in effective tumor cell lysis, during cytolytic granule polarization and subsequent exocytosis

Modifications:
Participates in complexes:
In compartment: Cytosol
  1. ITGAE:​ITGB7@Cytosol map
  2. ITGAE:​ITGB7@Cytosol map
Participates in reactions:
As Reactant or Product:
  1. ITGAE@Cytosol map + ITGB7@Cytosol map → map ITGAE:​ITGB7@Cytosol map
  2. ITGAE:​ITGB7@Cytosol map → map ITGAE:​ITGB7@Cytosol map
  3. E-Cadherin*|​hm2@Cytosol map + ITGAE:​ITGB7@Cytosol map → map E-Cadherin*|​hm2:​ITGAE:​ITGB7@Cytosol map
As Catalyser: