Identifiers
protein kinase, cGMP-dependent, type I
HUGO:PRKG1 HGNC:9414 ENTREZ:5592 UNIPROT:Q13976
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death / DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death / MITOCHONDRIAL_METABOLISM
Regulated Cell Death / NECROPTOSIS
References
PMID:12404124
Cyclic GMP-dependent inhibition of acid sphingomyelinase by nitric oxide: an early step in protection against apoptosis.
PMID:16716889
Maps_Modules
HMC:RESISTING_CELL_DEATH
HMC:DEREGULATING_CELLULAR_ENERGETICS
Regulated Cell Death / DEATH_RECEPTOR_PATHWAYS
Regulated Cell Death / MITOCHONDRIAL_METABOLISM
Regulated Cell Death / NECROPTOSIS
References
rc_re1564( Regulated Cell Death ):
PMID:12404124
nitric oxide inhibits acid and neutral sphingomyelinases through generation of cyclic GMP and activation of protein kinase G
rc_re1565( Regulated Cell Death ):
PMID:9393753
The protein kinase C activators phorbol esters and phosphatidylserine inhibit neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin.
PMID:26801188