Protein CD11a* map

Identifiers
HUGO:ITGAL

Maps_Modules
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Adaptive Immune Response  map  / SMAC  map
 Innate Immunity  map  / INTEGRINS  map

References
PMID:2150484
CASCADE:LFA1
 NATURAL_KILLER  map
PMID:10591186, PMID:24440149
LFA1 physically associates with DNAM1 in NK cells.
Phosphorylated by PKC S329 probably plays a critical role in this association.

Modifications:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CD11a*@INNATE_IMMUNE_CELL_Membrane map
Participates in complexes:
In compartment: INNATE_IMMUNE_CELL_Membrane
  1. CD11a*:​CD18*@INNATE_IMMUNE_CELL_Membrane map
  2. CD11a*:​CD18*:​DNAM1*|​pho@INNATE_IMMUNE_CELL_Membrane map
  3. CD11a*:​CD18*:​DNAM1*|​pho|​pho@INNATE_IMMUNE_CELL_Membrane map
In compartment: pSMAC
  1. CD11a*:​CD18*@pSMAC map
  2. CD11a*:​CD18*:​ICAM1:​TLN1@pSMAC map
Participates in reactions:
As Reactant or Product:
  1. CD11a*:​CD18*@pSMAC map + ICAM1@Cancer_cell map + TLN1@pSMAC map → map CD11a*:​CD18*:​ICAM1:​TLN1@pSMAC map
  2. DNAM1*|​pho@INNATE_IMMUNE_CELL_Membrane map + CD11a*:​CD18*@INNATE_IMMUNE_CELL_Membrane map → map CD11a*:​CD18*:​DNAM1*|​pho@INNATE_IMMUNE_CELL_Membrane map
  3. CD11a*:​CD18*:​DNAM1*|​pho@INNATE_IMMUNE_CELL_Membrane map → map CD11a*:​CD18*:​DNAM1*|​pho|​pho@INNATE_IMMUNE_CELL_Membrane map
  4. CD18*@INNATE_IMMUNE_CELL_Membrane map + CD11a*@INNATE_IMMUNE_CELL_Membrane map → map CD11a*:​CD18*@INNATE_IMMUNE_CELL_Membrane map
As Catalyser:
  1. TUBGCP2:​TUBGCP3:​TUBGCP4:​TUBGCP5:​TUBGCP6:​Tubulin-_alpha_*:​Tubulin-_beta_*:​Tubulin-_gamma_*@T_cell map + PXN|​pho@T_cell map → map PXN:​TUBGCP2:​TUBGCP3:​TUBGCP4:​TUBGCP5:​TUBGCP6:​Tubulin-_alpha_*:​Tubulin-_beta_*:​Tubulin-_gamma_*@T_cell map
  2. ERK1/2*@INNATE_IMMUNE_CELL_Cytosol map → map ERK1/2*|​pho@INNATE_IMMUNE_CELL_Cytosol map
  3. LCP2@INNATE_IMMUNE_CELL_Cytosol map → map LCP2|​pho@INNATE_IMMUNE_CELL_Cytosol map
  4. gFASL*@INNATE_IMMUNE_CELL_Cytosol map → map rFASL*@INNATE_IMMUNE_CELL_Cytosol map