Protein MAPKAPK* map

Identifiers
mitogen-activated protein kinase-activated protein kinase 2
HUGO:MAPKAPK2 HGNC:6887 ENTREZ:9261 UNIPROT:P49137
mitogen-activated protein kinase-activated protein kinase 3
HUGO:MAPKAPK3 HGNC:6888 ENTREZ:7867 UNIPROT:Q16644
mitogen-activated protein kinase-activated protein kinase 5
HUGO:MAPKAPK5 HGNC:6889 ENTREZ:8550 UNIPROT:Q8IW41

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / MAPK  map

References
MAPKAPK2 (MK2) MAPKAPK3 (MK3) and MAPKAPK5 (PRAK) are phosphorylated and activated by P38alpha and P38 beta. They catalyse phosphorylation of HSP27.
PMID:11274345

MAPKAPK*@Cytoplasm

References
su_mpk1_mpk1_re163( Survival  map ):
MAPKAPK2 and MAPKAPK3 are phosphorylated and activated by P38alpha and P38 beta.
PMID:11274345

MAPKAPK*|​pho@Cytoplasm

References
su_mpk1_mpk1_re163( Survival  map ):
MAPKAPK2 and MAPKAPK3 are phosphorylated and activated by P38alpha and P38 beta.
PMID:11274345
su_mpk1_mpk1_re164( Survival  map ):
MAPKAPK2 MAPKAPK3 and PRAK catalyse phosphorylation of HSP27.
su_mpk1_mpk1_re188( Survival  map ):
P38 is able to suppress RAS-dependent JNK activation (probably through PRAK and MK2).
PMID:10978313

Modifications:
In compartment: Cytoplasm
  1. MAPKAPK*@Cytoplasm map
  2. MAPKAPK*|​pho@Cytoplasm map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. MAPKAPK*@Cytoplasm map → map MAPKAPK*|​pho@Cytoplasm map
    As Catalyser:
    1. HSPB1@Nucleus map → map HSPB1|​pho@Nucleus map
    2. JNK*|​pho|​pho@Cytoplasm map → map JNK*@Cytoplasm map