Identifiers
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
HUGO:MMP3, HGNC:7173, ENTREZ:4314, GENECARDS:GC11M102706??
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / ECM
Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / EMT_REGULATORS
EMT Senescence / ECM
References
em_emtc_emtc_re63( EMT Senescence ):
PMID:10048576
The gene expressions of MMP-1, MMP-3, and MMP-9 and gelatinolytic activity of MMP-9 were significantly increased in high ETS-1 expression cells.
Low ETS-1 expression cells could not spread on a vitronectin substratum, and the phosphorylation of focal adhesion kinase was markedly impaired because of the reduced expression of integrin b3
PMID:15003528
NF-kappaB binds to a polymorphic repressor element in the MMP-3 promoter.