Protein WNT3 map

Identifiers
wingless-type MMTV integration site family, member 3
INT4
HUGO:WNT3 HGNC:12782 ENTREZ:7473 UNIPROT:P56703 GENECARDS:WNT3 REACTOME:67380 KEGG:7473 ATLASONC:GC_WNT3 WIKI:WNT3

Maps_Modules
HMC:EVADING_GROWTH_SUPPRESSORS
 Survival  map  / WNT_NON_CANONICAL  map

WNT3@default

References
Wnt1 and Wnt3 can bind to ROR2
PMID:18762249, PMID:14960582
Both Wnt ligands can reduce b-catenin/TCF/LEF transcription via NLK
PMID:18762249, PMID:20194509

Modifications:
In compartment: default
  1. WNT3@default map
Participates in complexes:
In compartment: Cytoplasm
  1. FZD*:​ROR2:​WNT3@Cytoplasm map
  2. FZD*:​ROR2|​pho:​WNT3@Cytoplasm map
  3. FZD*:​ROR2|​pho:​TAB1:​TAB2:​TAK1*|​pho:​WNT3@Cytoplasm map
Participates in reactions:
As Reactant or Product:
  1. FZD*:​ROR2:​WNT3@Cytoplasm map → map FZD*:​ROR2|​pho:​WNT3@Cytoplasm map
  2. TAB1:​TAB2:​TAK1*|​pho@Cytoplasm map + FZD*:​ROR2|​pho:​WNT3@Cytoplasm map → map FZD*:​ROR2|​pho:​TAB1:​TAB2:​TAK1*|​pho:​WNT3@Cytoplasm map
  3. FZD*:​ROR2|​pho:​TAB1:​TAB2:​TAK1*|​pho:​WNT3@Cytoplasm map → map WNT canonical pathway@Cytoplasm map
  4. WNT3@default map + ROR2@Cytoplasm map + FZD*@Cytoplasm map → map FZD*:​ROR2:​WNT3@Cytoplasm map
As Catalyser: