Protein BIRC3 map

Identifiers
baculoviral IAP repeat containing 3
HUGO:BIRC3 hgnc_id:HGNC:591 HGNC:591 ENTREZ:330 UNIPROT:Q13489
HUGO:BIRC3 HGNC:591 ENTREZ:330 UNIPROT:Q13489
HUGO:BIRC3

Maps_Modules
HMC:TUMOR_PROMOTING_INFLAMMATION
HMC:ACTIVATING_INVASION_AND_METASTASIS
 Cancer Associated Fibroblasts  map  / INFLAMMATORY_SIGNALING_PATHWAYS  map
HMC:RESISTING_CELL_DEATH
 Regulated Cell Death  map  / DEATH_RECEPTOR_PATHWAYS  map
 Regulated Cell Death  map  / TNF_RESPONSE  map
HMC:AVOIDING_IMMUNE_DESTRUCTION
 Innate Immunity  map  / IMMUNOSTIMULATORY_CYTOKINE_PATHWAYS  map

References
PMID:21232017, PMID:21133840, PMID:17301840
cIAP1 and cIAP2 modify RIP1, TRAF2 and themselves with K63-linked ubiquitin chains. This creates docking sites for the LUBAC complex, an E3 ligase capable of forming linear polyubiquitin chains.

Modifications:
In compartment: Cytosol
  1. BIRC3@Cytosol map
In compartment: INNATE_IMMUNE_CELL_Cytosol
  1. BIRC3@INNATE_IMMUNE_CELL_Cytosol map
Participates in complexes:
    Participates in reactions:
    As Reactant or Product:
    1. BIRC3@Cytosol map → map cIAP*@Cytosol map
    2. BIRC3@INNATE_IMMUNE_CELL_Cytosol map → map cIAP*@INNATE_IMMUNE_CELL_Cytosol map
    3. BIRC3@Cytosol map → map cIAP*@Cytosol map
    4. rBIRC3@Nucleus map → map BIRC3@Cytosol map
    As Catalyser: