Maps_Modules
HMC:ACTIVATING_INVASION_AND_METASTASIS
EMT Senescence / LYSOSOME_ENDOSOME
References
PMID:22674073
E-cadherin does not travel directly from the Golgi complex to the cell surface, but transits first through Rab11-positive recycling endosomes. Rab11 is involved in E-cadherin localization to the surface of the cell .
In addition to acting as way stations for newly synthesized cadherin on its way to the plasma membrane, Rab11-positive recycling endosomes can also sort internalized cadherin for recycling back to the cell surface.
Desclozeaux and colleagues also found that cadherin recycling is necessary for maintaining adherens junctions.
References
em_re1497( EMT Senescence ):
PMID:22674073
E-cadherin does not travel directly from the Golgi complex to the cell surface, but transits first through Rab11-positive recycling endosomes. Rab11 is involved in E-cadherin localization to the surface of the cell .
In addition to acting as way stations for newly synthesized cadherin on its way to the plasma membrane, Rab11-positive recycling endosomes can also sort internalized cadherin for recycling back to the cell surface.
Desclozeaux and colleagues also found that cadherin recycling is necessary for maintaining adherens junctions.