Protein DDB1
Identifiers
Damage-specific DNA binding protein 1, 127kDa, XPE, p48
HUGO:DDB1, HGNC:2717, ENTREZ:1642, UNIPROT:Q16531
damage-specific DNA binding protein 1, 127kDa
Maps_Modules
HMC:GENOME_INSTABILITY_AND_MUTATION
Cell Cycle DNA Repair
/ NER
HMC:RESISTING_CELL_DEATH
Regulated Cell Death
/ STARVATION_AUTOPHAGY
References
PMID:20211143, PMID:19809470, PMID:1570337, PMID:19847258, PMID:16697054, PMID:12648680, PMID:17884153, PMID:11900249
Modifications:
In compartment: Nucleus
- DDB1@Nucleus
Participates in complexes:
In compartment: Cytosol
- CUL4A:DDB1:RBX1:_beta_TRCP*@Cytosol
In compartment: Nucleus
- CSA*:CUL4*:DDB1:RBX1@Nucleus
- CUL4*:DDB1:DDB2:RBX1@Nucleus
Participates in reactions:
As Reactant or Product:- RBX1@Nucleus
+ CUL4*@Nucleus
+ DDB1@Nucleus
+ CSA*@Nucleus
→
CSA*:CUL4*:DDB1:RBX1@Nucleus
- DDB2@Nucleus
+ RBX1@Nucleus
+ CUL4*@Nucleus
+ DDB1@Nucleus
→
CUL4*:DDB1:DDB2:RBX1@Nucleus
As Catalyser:- TC-NER_DNA_st1*:Transcription machine_br_(RNAPII)*@Nucleus
→
Transcription machine_br_(RNAPII)*@Nucleus
+ gTC-NER_DNA_st2*@Nucleus
- gGG-NER_DNA_st1*@Nucleus
→
gGG-NER_DNA_st2*@Nucleus
- DDIT4|pho@Cytosol
→
DDIT4|pho|ubi@Cytosol